COVID-19 is also an acute inflammatory process, with the aggravation of COVID-19, biochemical indicators in patient’s body changed.5 Laboratory results indicated that lactate dehydrogenase (LDH) and c-reactive protein (CRP) may be elevated in patients with COVID-19, and procalcitonin (PCT) may be normal.6 Previous literatures had suggested that AST, LDH, CRP, and PCT were associated with the prognosis of some inflammatory diseases.7, , , , –12 However, Whether these makers can identify the patients whose nucleic acid could turn negative during the quarantine (14 days) has not been reported. Here, CRP is linked to COVID-19.