PVT1 and Burkitt lymphoma: PVT1 gene was first discovered in mice in 1983 and is often associated with plasmacytoma.[23,24] Shortly after that, the PVT1 locus also appeared as a variant translocation site in human Burkitt lymphoma.[25] Since then, as reflected in the increase in terms of the number of PVT1-related publications, PVT1 has been a focus area, especially in recent decades.