Abnormality of PDGFRB gene is associated with chronic myeloid leukemia (CML), acute myelogenous leukemia (AML), chronic myelomonocytic leukemia (CMML), acute lymphocytic leukemia (ALL), chronic eosinophilic leukemia (CEL), myeloproliferative disease (MPD), and other diseases. The gene discussed is PDGFRB; the disease is chronic myelomonocytic leukemia.