Pericarditis is probably the consequence of pro-inflammatory cytokine storm in COVID-19 infection.[11] Current data revealed high concentrations of interleukin-1 beta, interferon gamma, interferon inducible protein-10, interleukin-6 and monocyte chemoattractant protein-1 in patients with COVID-19 infection.[21] This inflammatory damage mediated by overactivation of the immune system is suggested by sporadic autopsy cases showing infiltration of myocardium by interstitial mononuclear inflammatory cells[22] and the patient's good response to glucocorticoid treatment.[23]. This evidence concerns the gene IFNG and pericarditis.