Therefore, to test the effect of CAM833 on RAD51 clustering, we used SMLM on patient-derived EUFA423 cells (Figure 4A) bearing compound heterozygosity for the cancer-associated BRCA2 truncating alleles 7691insAT and 9000insA (Haas et al., 2018; Howlett et al., 2002). The gene discussed is BRCA2; the disease is cancer.