The risk for possible sarcopenia was greater among individuals with hypertension(OR1.29; 95% CI 1.13–1.48), heart disease (OR 1.24; 95% CI 1.05–1.47) or high concentration of CRP(OR1.02; 95%CI 1.01–1.03) in rural populations, whereas hemoglobin (OR 0.96; 95% CI 0.92–0.99) was negatively associated with the risk of possible sarcopenia in rural populations. This evidence concerns the gene CRP and sarcopenia.