CRP and hypertensive disorder: Wang and colleagues developed (n = 296) and validated (n = 44) two models, both based on age: one clinical (including age, hypertension and coronary heart disease sensitivity), and one based on laboratory parameters [age, C-reactive protein, SpO2, neutrophil and lymphocyte count, D-dimer, aspartate aminotransferase (AST) and GFR] which had a significantly stronger discriminatory power than the clinical model [28].