As shown in Table 2, age, diabetes mellitus (DM), hypertension, AST, ALT, thrombocytopenia, hypoalbuminemia, liver cirrhosis, Child Pugh grade, tumor number, tumor size, histology stage, vascular invasion, higher Ishak fibrosis score, hepatitis C were significantly associated with HCC recurrence in univariate analysis. The gene discussed is GPT; the disease is hepatocellular carcinoma.