A significant correlation was found between MUC5b concentration and Reliefmax (p = 0.023) and Relief period (p = 0.005) in saliva from patients treated with radiotherapy (Fig. 3b, c), while protein concentration correlated with Reliefmax in both patients with pSS and patients treated with radiotherapy (p = 0.023 and p = 0.002 respectively) (Fig. 3d). Here, MUC5B is linked to peeling skin syndrome.