There have also been numerous reports of overexpression and single-nucleotide variants in PIK3CG linked to cancer development in multiple tissues (Torres et al., 2019; Dituri et al., 2012; Edling et al., 2010; Ge et al., 2019; Zhang et al., 2019; Nava Rodrigues et al., 2018; Shu et al., 2018; Wang et al., 2020). The gene discussed is PIK3CG; the disease is cancer.