TMPRSS2 and congestive heart failure: In RV, and in similarity with its behaviour in the lung and LV tissues, TMPRSS2 expression was downregulated in CHF animals, especially in the decompensated subgroup, in comparison with sham‐operated animals (0.15 ± 0.02 vs 1.0 ± 0.23; P < .01, respectively) (Figure 4G).