INS and type 2 diabetes mellitus: Principally, our findings indicate that there is no relationship between fasting [glucose] or [insulin], or the responsiveness of each variable to an OGTT, with skeletal muscle microvascular endothelial function; however, we report for the first time a moderate correlation between HbA1c and skeletal muscle microvascular endothelial function in patients with T2DM (Figures 1 and 2).