We found that MYCN levels and activity have a direct effect on fatty acid amount, as well as on glucose as the preferred carbon source for fatty acid synthesis in neuroblastoma, in agreement with our earlier results (Oliynyk et al., 2019) and studies in other MYC-driven tumors (Eberlin et al., 2014; Edmunds et al., 2014; Morrish et al., 2010; Gouw et al., 2019). Here, MYCN is linked to neuroblastoma.