On thecontrary, some studies did not detect a significant associationof ARG1 gene polymorphisms with the efficacy of asthmatherapies (Almomani et al., 2019; Scaparrotta et al., 2019).Together, this results and literature data confirm that ARG1gene allelic variants can contribute to asthma pathogenesisand the effectiveness of disease therapy. The gene discussed is ARG1; the disease is asthma.