TP53 and breast carcinoma: A more detailed study of Zheng et al. (47) on Nigerian women established that up to 20% of inherited invasive breast cancer cases in Nigeria are associated with inherited mutations in BRCA1, BRCA2, PALB2, or TP53. Their findings on BRCA1 and BRCA2 built on the earlier report of Fackenthal et al. (48) that Nigerian breast cancer patients have a very high frequency of BRCA1 and BRCA2 mutations.