ALK and non-small cell lung carcinoma: An ongoing trial, ALTA-3 (https://clinicaltrials.gov/ number, NCT03596866), compares the efficacy of alectinib versus brigatinib in ALK+ NSCLC patients who had progressed on crizotinib; besides, and according to the current lack of direct comparisons, indirect analyses using available data have been performed to compare them.