Furthermore, soluble CD52 was significantly elevated in SLE patients with detectable levels of C-Reactive Protein (≥ 0.2 mg/dl), an inflammatory marker, compared to those with trace amounts (< 0.2 mg/dl) (median [IQR] of trace vs. detectable: 7.805 [7.165, 9.295] vs. 12.16 [10.13, 16.47] ng/ml; p = <0.0001) (Figure 2C). Here, CRP is linked to systemic lupus erythematosus.