STAT3 and colorectal carcinoma: ETV5 overexpression stimulates CRC angiogenesis through activation of VGFR by PDGFR-β/Src/STAT3 signaling (Llaurado et al., 2012) and increases bevacizumab resistance through AKT, ERK, and p38 signaling decreasing overall survival of the patients (Llaurado et al., 2012).