VEGFA and coronary artery disorder: Our group had previously predicted the underlying pharmacological mechanism of Xueshuan-Xinmai-Ning (XXNT) acting on coronary heart disease (CHD) through network pharmacology method, and found that the XXNT in the treatment of CHD might be involved into the signal transduction in nervous-endocrine-immune-cardiovascular-metabolic system, and it is verified by experiments that XXNT plays a role in treating CHD via VEGF signal pathway (Mao et al., 2019).