In addition, core binding factor acute myeloid leukemia (CBF-AML), nucleophosmin 1 (NPM1) and fms related receptor tyrosine kinase 3 (FLT3) in risk stratification have no impact on the expression of BRD4, PD-L1 and PD-1 (Supplementary Figures S1A–C). Here, NPM1 is linked to acute myeloid leukemia.