PTHLH and familial pancreatic carcinoma: Given our findings that BRDT colocalized with ΔNp63 on several genes such as FAT2 and PTHLH, which we previously demonstrated as being associated with ΔNp63-dependent SEs in pancreatic cancer [28], we investigated whether BRDT, like BRD4, may be a defining feature of SEs in a subset of ESCC.