Given our observation that BRDT was required for cell migration, we hypothesized that depletion of either the responsible transcription factor providing sequence specificity to BRDT activity (ΔNp63) or a downstream ΔNp63/BRDT target previously shown to control cell migration in human squamous carcinoma cells (FAT2) [51], may phenocopy the effects of BRDT depletion on cell migration. The gene discussed is BRDT; the disease is squamous cell carcinoma.