Although first described as part of our innate immunity and induced by microbial pathogens, several other “NET inducers” have been proposed, including a plethora of factors also associated with the tumor microenvironment, including soluble P-selectin (sP-selectin)24, interleukin-8 (IL-8)25, and granulocyte-colony stimulating factor (G-CSF)26. The gene discussed is CXCL8; the disease is neoplasm.