Expression of the maintenance DNA methyltransferase DNMT1 is lower in LOX IMVI melanoma cells relative to 72 percent of NCI-60 cell lines, while expression of the de novo DNA methyltransferase DNMT3A is higher in LOX IMVI cells relative to 80 percent of cell lines in the NCI-60 panel7 (Supplementary Data 2). Here, DNMT3A is linked to melanoma.