Based on our observation that PP2A dephosphorylates MCL-1 at Ser159/Thr163 (Fig. 5A), which was also shown by others in lymphoma cells46, we studied the kinases that can phosphorylate MCL-1 at these residues: GSK-3, ERK-1, and JNK. The gene discussed is MAPK8; the disease is lymphoma.