The results showed alterations in UHRF1, EZH2, TTF2, SUV39H2, PCNA, WHSC1/NSD2 and RAD54L genes with a frequency of 0.5%, 2.8%, 3%, 1.3%, 1.4%, 2.4% and 1.7%, respectively, in NSCLC patient samples (n=1144; Figure 7). This evidence concerns the gene NSD2 and non-small cell lung carcinoma.