SUV39H2 expression was significantly upregulated in large cell lung carcinoma (fold change=3.479; P=7.63E-09), lung adenocarcinoma (fold change: 2.056; P=1.12E-13), and squamous cell lung carcinoma (fold change: 2.476; P=1.67E-15) tissues compared to the normal lung tissues from the Hou lung dataset, and large cell lung carcinoma tissues (fold change=2.435; P=8.00E-03) from the Garber lung dataset. Here, SUV39H2 is linked to squamous cell lung carcinoma.