WHSC1 was significantly over-expressed in the squamous cell lung carcinoma tissues from the Wachi lung dataset (fold change=2.146; P=8.13E-04) and Bhattacharjee lung dataset (fold change=2.448; P=4.00E-03), lung adenocarcinoma tissues (fold change=3.702; P=6.18E-07) from the Su lung dataset, and large cell lung carcinoma tissues (fold change=2.913; P=7.87E-07) from the Hou lung dataset. This evidence concerns the gene NSD2 and lung large cell carcinoma.