NLRP1 and neoplasm: In terms of lung tissue, the functional research of NLRP1 mainly focused on non-tumor diseases, such as: the NLRP1 inflammasome initiates pyroptosis, which subsequently leads to a self-amplifying cascade of cell injury within the lung [23]; the fine-tuning of the NLRP1 inflammasome plays an important role in maintaining the lung tissue integrity and treating the chronic inflammation of the airway [24]; the activation of the NLRP1 inflammasome pathways contributes to pulmonary fibrosis caused by latent MCMV infection in mice [25].