IFNA1 and Zika virus infectious disease: The observation that TLR3 activation by ZIKV induces proinflammatory cytokines at the expense of the IFN response, along with data showing robust activation of a TLR3-dependent immune response in hNPCs after poly(I·C) stimulation (40), led us to investigate whether TLR3 signaling might suppress the IFN response upon ZIKV infection in neural progenitor cells.