Therefore, the functional assessment of polymicrogyria candidate genes, for example, 1p36 candidates, α-enolase encoding ENO1, and arginine–glutamic acid dipeptide repeats protein-encoding RERE (Jordan et al, 2015; El Waly et al, 2020), in the context of NB can be very informative. The gene discussed is RERE; the disease is neuroblastoma.