NUCB1 and neuroblastoma: While IKNM was not amenable to examination in dissociated cultures because of the absence of adherens junctions present in vivo (LaMonica et al, 2013), differential knockdown (KD) of DCX, controlling G1-specific, kinesin-dependent NUC (Carabalona et al, 2016), and of LIS1, controlling G2-specific, dynein-dependent NUC, and spindle assembly during IKNM (Tsai et al, 2005; Yingling et al, 2008; Carabalona et al, 2016), could help to tell IKNM from NUC in NB.