Lysosome-associated membrane protein 3 (LAMP3) is a membrane glycoprotein predominantly localised in lysosomes that is reported to be induced by IFN.10 In aggregated microarray studies, increased expression of LAMP3 is detected in the salivary glands of patients with SS compared with control glands.11 However, its causal relationship to the development of SS-associated symptoms is not clear. The gene discussed is IFNA1; the disease is synovial sarcoma.