In this study, 44 potential targets were obtained through the intersection of the disease targets of COVID-19 and the action targets of AE, which are mainly related to inflammatory or immune factors, such as IL-6, MAPK1, MAPK8, IL1B, RELA, CXCL-8, CCL2, and PTGS2. The gene discussed is MAPK8; the disease is COVID-19.