Specifically, BMPER is associated with body mass index (BMI); TOMM40/APOE is associated with low‐density lipoprotein cholesterol (LDL‐C), high‐density lipoprotein cholesterol (HDL‐C), total cholesterol (TC), total triglyceride (TG), and colorectal cancer (CRC), and TMEM43 is associated with aspartate aminotransferase (AST) and blood uric acid (UA). This evidence concerns the gene TMEM43 and colorectal carcinoma.