HLA‐C*12:02 is a susceptibility factor in the late‐onset type of psoriasis in Japanese (Mabuchi et al., 2014), while HLA‐B*52:01 has been reported to increase the risks of pulmonary infarction, ischemic heart disease, aortic regurgitation, hypertension, renal artery stenosis, cerebrovascular disease, and visual disturbance (Kitamura et al., 1998). The gene discussed is HLA-B; the disease is aortic valve insufficiency.