BMPER and early-onset autosomal dominant Alzheimer disease: In addition, we found that the Alzheimer's disease‐related SNP rs17169634 in BMPER was the longevity marker showing the greatest promoting effect, with carriers of the minor allele G exhibiting a substantially longer life span than noncarrier (28.3% for GG, 16.8% for GA, and 11.3% for AA; survival HR = 1.25; p = 1.45 × 10−10; Figure 4B).