In addition, studies have shown that the expression of MHC class II transactivator (CIITA) in EB virus‐positive diffuse large B‐cell lymphoma (DLBCL) is significantly reduced compared with that in EB virus‐negative DLBCL and that gene aberrations involving CIITA are more common in EBV + DLBCL.79 The gene discussed is CIITA; the disease is diffuse large B-cell lymphoma.