As shown above, RRV 26–95 infection was enhanced by both Plxcd1 and Plxdc2 expression (Fig 2E and 2H) and similarly RRV 26–95 gH/gL or gH alone facilitated fusion with Plxdc1 or Plxdc2 overexpressing Raji cells (Fig 6E). Here, PLXDC1 is linked to infection.