EphA7, which had previously been described by our group to be critical for RRV infection of BJAB B lymphocytes enhanced RRV-YFP wt infection to 44.4% while infection with the Eph-binding-negative mutant RRV-YFP gH-AELAAN was not affected (Fig 2E and 2H). The gene discussed is EPHA7; the disease is infection.