We demonstrated that RRV infection of select cell lines exhibits a dependence on specific receptors, e.g. Raji infection—to the modest extent that was possible without recombinant receptor overexpression—was dependent on the gH/gL-Eph interaction, while MFB5487 infection was more dependent on the Plxdc-interaction (Fig 5B). This evidence concerns the gene EPHA1 and infection.