MMP8 and Cirrhosis: Thus, surface‐bound MMP‐8 on LPS‐activated monocytes and macrophages could be targeted therapeutically to decrease macrophage tissue infiltration in diseases in which macrophages promote disease progression including idiopathic pulmonary fibrosis and hepatic cirrhosis (Baig et al., 2016; Craig et al., 2014; Tacke, 2017).