Our data also highlight the proteins encoded by AGR2, AHNAK, CD36, CRYAB, DCN, HSPA2, LCPN1, PFN1, PRKDC, PTGIS, SLC9A3R1, THBS1, TNC and TNXB genes as DEPs between the male and female breast tumors. The gene discussed is PTGIS; the disease is breast neoplasm.