A previous study reported that decreased lncRNA H19 expression increases miRNA let-7 activity by acting as a molecular sponge and then reduces the proliferation of endometrial stromal cells via insulin-like growth factor (IGF) signaling in eutopic endometrium of women with endometriosis, which may contribute to impaired endometrial receptivity for implantation and is associated with infertility (26). This evidence concerns the gene H19 and endometriosis.