CD274 and neuroblastoma: Meta-analysis was performed using Stata 15.0 software.<h4>Results</h4>This review will be disseminated in print by peer-review.<h4>Conclusion</h4>The study will provide updated evidence for the evaluation of whether the expression of PD-L1 is associated with poor prognosis in patients with neuroblastoma.<h4>Ethics and dissemination</h4>The private information from individuals will not be published.