The combined ORs of epilepsy were 1.46 (95% CI, 1.18, 1.82) for one unit increase in log OR of having depression, 1.44 (95% CI, 1.13, 1.85) for one standard deviation increase in serum ferritin, 1.12 (95% CI, 1.04, 1.21) for one standard deviation increase in transferrin saturation, and 1.25 (95% CI, 1.09, 1.43) for one standard deviation increase in the prevalence of smoking initiation. This evidence concerns the gene TF and depressive disorder.