The variables that were predictive of mortality only included age, CAD, hypertension, CKD, COPD, statin, aspirin, and anticoagulant use, lower levels of hemoglobin and platelets, and elevated levels of creatinine, mean corpuscular volume (MCV), NT-ProBNP, and increased red cell distribution and width (RDW). This evidence concerns the gene NPPB and chronic obstructive pulmonary disease.