C-reactive protein (CRP), procalcitonin, presepsin, etc are examples of such markers that have been widely studied [3-5]. However, these conventional inflammatory markers such as CRP, erythrocyte sedimentation rate (ESR), and white blood cell count (WBC), have proven to have a limited utility in sepsis patients by virtue of their poor sensitivity and specificity for infections. The gene discussed is CRP; the disease is infection.