Thus, BRD4-CDK9 axis induces RNAP2-mediated transcription of SE/E-driven oncogenes, including MYC, BCL2, Bcl-xL and CDK4/6, which are important for cell growth and survival of RT-DLBCL cells [19, 24, 25]. Here, BCL2 is linked to diffuse large B-cell lymphoma.