QPCR analysis showed that OTX015 treatment inhibited mRNA levels of the super-enhancer-driven MYC and CDK6 oncogenes, while inducing HEXIM1 mRNA levels in all three RT-DLBCL cell-types (Fig. S5E and Table S10) [20, 47]. This evidence concerns the gene HEXIM1 and diffuse large B-cell lymphoma.