Therefore, it is possible that these additional functional effects of PPARG and PGC1a are, along with PPARG’s ability to increase exogenous fatty acid uptake [36, 37], synergistic with the mitochondrial biogenesis effects of PPARG, and could account for some additional functions of PPARG in prostate cancer not attributable to AKT3. Here, PPARGC1A is linked to prostate carcinoma.