Depletion of CLPTM1L and Akt phosphorylation at T308 and cleavage of Caspase-3 upon treatment of A549, NCI-H520, and NCI-H226 lung cancer cell lines with 102-5 anti-CLPTM1L are shown in Supplementary Fig. 5a–c. This evidence concerns the gene CLPTM1L and lung cancer.