CASP3 and familial pancreatic carcinoma: Depletion of CLPTM1L and Akt phosphorylation at T308 and cleavage of Caspase-3 upon treatment of Panc1, MiaPaca2, and Capan2 pancreatic cancer cell lines with 102-5 anti-CLPTM1L are shown in Supplementary Fig. 5d–f.