CYLD and nasopharyngeal carcinoma: The expression of CYLD in EBV-uninfected and EBV-infected cells was examined and results showed that mRNA and protein levels of CYLD were significantly reduced in the EBV- infected immortalized nasopharyngeal epithelial cell lines, NP460hTERT-EBV, and also the nasopharyngeal carcinoma cell line, HK1-EBV and HONE1-EBV (Fig. 1e, f).