To compile a model-independent systematic analysis of the tumor immune effects of the obese environment, we investigated five syngeneic cell line tumor models in two cancer types (mammary adenocarcinoma: E0771, TeLi and Wnt1; pancreatic ductal adenocarcinoma: C11 and UN-KC; Table 1). This evidence concerns the gene CALCA and pancreatic ductal adenocarcinoma.