CSF2 and neoplasm: Secretion of IL-17 by γδT cells is accompanied by upregulation of the expression of granulocyte–macrophage colony-stimulating factor (GM-CSF), which leads to accumulation of polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) [70] and tumor-associated neutrophils (TANs) [75] at tumor sites.