TGFB1 and Headache: Using ANCOVA controlled for baseline TGF-β levels, age, sex, BMI changes, years of having headache and number of days from the last headache attack showed significantly elevated serum levels of this cytokine in the intervention arm (adjusted mean: 1665.50 ng / L) than in placebo group (adjusted mean: 1361.90 ng /L) (P-value = 0.012).