Previously we demonstrated that miR-214 downregulates N-ras to promote myogenic differentiation at the expense of osteogenic differentiation [17]; however, genetic ablation of miR-214 did not lead to obvious signs of Noonan syndrome-like features including growth delay in mice [18, 19] (Additional file 2: Fig. S1). The gene discussed is NRAS; the disease is Noonan syndrome.