Similarly, in LMP1-expressing nasopharyngeal epithelial cells, increased expression of SREBP1 mediates lipogenesis through mammalian target of rapamycin (mTOR) signalling; the induction of lipid synthesis promotes cell growth in EBV-driven cancers, and when inhibited, there is a suppression of growth and an increase in apoptosis in NPC cells [21]. This evidence concerns the gene PDLIM7 and nasopharyngeal carcinoma.