Within the Hallmark gene set, EMT and P53 pathway genes were strongly enriched, as were the TGF-β, Wnt/β-catenin, TNFα (via NFkB), and Notch signaling pathways, indicating that EMT and its related signaling pathways were activated in these ATF3 mammary tumors. The gene discussed is NFKB1; the disease is breast cancer.